WARNING: THIS ARTICLE CONTAINS SPOILERS.

The newly released Netflix series, House of Guinness, delves into the history of the globally renowned Guinness family, including Arthur Guinness.

Upon the death of the family patriarch, his will and the distribution of his assets sparked a fierce divide amongst his children, including Edward Guinness.

In the series, his daughter Anne (portrayed by Emily Fairn) was not bequeathed a share in the brewery business. Instead, she developed a passion for aiding the disadvantaged and ill.

Anne herself battled a mysterious illness, confessing to her brothers that she had observed changes in her body and often felt out of control, reports the Irish Mirror.

These physical alterations were also noticed by those she encountered, who remarked on her difficulty walking.

A distressing scene in the series sees Anne suffer a miscarriage, although it is not believed to be connected to her illness.

In reality, Anne was afflicted with a degenerative disease and passed away at the tender age of 50.

Her condition was chronic, causing her suffering for a significant part of her life, though its specific name has not been disclosed.

Present-day degenerative conditions include Alzheimer’s, Parkinson’s and motor neurone disease.

Anne is remembered for her kindness and readiness to assist others. While her father was restoring St Patrick’s Cathedral in Dublin, she became involved in initiatives supporting the poor and sick in the area.

She was a patron of bible readings and basic medical supplies, and later founded St Patrick’s nursing home in 1876, which evolved into a training centre for Church of Ireland nurses.

Anne married William Plunket, Archbishop of Dublin in 1863, and they were blessed with six children.

William was a staunch supporter of Anne’s work, and her memory is honoured with a series of stained-glass windows at St Patrick’s Cathedral.

House of Guinness is on Netflix